@charset "utf-8";


/* section */

section {
    padding: 60px 0;
    padding: 3.75rem 0;
    padding-bottom: 2.5rem;
    overflow: hidden;
}

section .section-title h2 {
    font-family: 'M PLUS Rounded 1c', 'Noto Sans JP', sans-serif;
    font-weight: 700;
    color: #000;

    /*font-size: 42px;
    font-size: 2.625rem;
    font-size: 2.125rem;*/
    font-size: 30.6px;
    margin-bottom: 46px;
    margin-bottom: 2.875rem;
    margin-bottom: 2.25rem;
    margin-bottom: 2rem;
}


section .section-title h2.text-green {
    color: var(--theme-color1);
}



/* main-banner jumbotron */

section#main-banner.jumbotron {
    margin-bottom: 0;
    padding-left: 0;
    padding-right: 0;
    padding: 3rem 0;
    /*background-image: url(images/main_banner_back.png);*/
    background-repeat: no-repeat;
    background-size: cover;
    border-radius: 0;
}

section#main-banner h1.main-title {
    font-size: 120px;
    font-size: 7.5rem;
    font-family: 'M PLUS Rounded 1c', sans-serif;
    font-weight: 700 !important;
    letter-spacing: -0.15rem;
    color: #000;
    margin-bottom: 0.5rem;
    line-height: 7.5rem;
}

section#main-banner p.main-subtitle {
    font-size: 17px;
    font-size: 1.0625rem;
    font-weight: 500 !important;
    margin-bottom: 3rem;
    /*letter-spacing: -0.15rem;*/
    color: #818181;
}

section#main-banner div .btn {
    /*border-radius: 23px;
    font-size: 1.1875rem;
    color: #fff;
    font-weight: 500;
    height: 46px;
    line-height: 46px;
    padding: 0;
    transition: all 0.3s ease;*/
}

section#main-banner div.main-search input {
    border-radius: 23px;
    font-size: 1.1875rem;
    font-weight: 500;
    height: 46px;
    line-height: 46px;
    padding: 0;
    padding-left: 1.375rem;
}

section#main-banner div.main-search input {
    border-top-right-radius: 0;
    border-bottom-right-radius: 0;
}

section#main-banner div.main-search input::placeholder {
    font-family: 'M PLUS Rounded 1c', 'Noto Sans JP', sans-serif;
    color: #757575 !important;
    color: #a2a2a2 !important;
    color: transparent;
    font-size: 1.0625rem;
    font-weight: 400 !important;
}

html:lang(ja) section#main-banner div.main-search input::placeholder {
    font-weight: 300 !important;
}

section#main-banner div.main-search input:focus::placeholder {
    color: transparent;
}


section#main-banner div.main-search .btn {
    border-top-left-radius: 0;
    border-bottom-left-radius: 0;
}

section#main-banner div.main-search .input-group {
    max-width: 500px;
}

section#main-banner div.main-search .btn-search {
    width: 80px;
}

section#main-banner div .btn span {
    font-size: 16px;
    font-size: 1rem;
    font-weight: 400;
}


section#main-banner div .btn:hover {
    /*background-color: #d70a30;
    border-color: #d70a30;*/
    /*transform: translateY(-3px);
    box-shadow: 0px 6px 14px 0px rgb(0 0 0 / 15%);*/
}

section#main-banner div .btn:active {
    /*color: #fff;
    background-color: #ffa526;
    border-color: #ffa526;*/
    /*box-shadow: none;
    border: none;
    outline: none;*/
}

section#main-banner div.main-banner-image img,
section#about div.main-banner-image img {
    transition: all 0.6s ease;
}

section#main-banner div.main-banner-image img:hover,
section#about div.main-banner-image img:hover {
    transform: translateY(-4px);
    /*cursor: pointer;*/
    /*box-shadow: 0px 6px 14px 0px rgb(0 0 0 / 15%);*/
}


/* アイコンの初期状態（プラスアイコン） */
.toggle-icon[aria-expanded="false"] i::before {
    content: "\f0fe";
    /* Font Awesomeのプラスアイコン（fa-plus） */
}

/* 開いた状態（マイナスアイコン） */
.toggle-icon[aria-expanded="true"] i::before {
    content: "\f146";
    /* Font Awesomeのマイナスアイコン（fa-minus） */
}

.collapse-amin {
    transition: height 0.4s ease;
}

/*
.collapse {
    display: block !important;
    height: 0 !important;
    overflow: hidden !important;
    transition: height 0.35s ease;
}

.collapse.show {
    height: auto !important;
}
*/

/* nav */

nav .nav-back {
    display: none;
}



/* map */


/* Small devices (landscape phones, 576px and up)*/
@media (min-width: 576px) {}

/*Medium devices (tablets, 768px and up)*/
@media (min-width: 768px) {
    img.search-map {
        max-width: 580px;
    }
}

/* Large devices (desktops, 992px and up)*/
@media (min-width: 992px) {
    img.search-map {
        max-width: 400px;
    }
}

/* X-Large devices (large desktops, 1200px and up)*/
@media (min-width: 1200px) {
    img.search-map {
        max-width: 400px;
    }
}

/* XX-Large devices (larger desktops, 1400px and up)*/
@media (min-width: 1400px) {
    img.search-map {
        max-width: 400px;
    }
}



/* about */

section#about {
    /*background-color: #fff;*/
}

section#about p.about-text {
    font-size: 22px;
    font-size: 1.375rem;
    font-weight: 400;
}

section#about p.about-subtext {
    /* font-size: 0.9rem; */
    font-size: 1rem;
    font-weight: 400;
}

section#about p strong {
    font-weight: 600;
}

section#about p.acronym {
    font-size: 1.1875rem;
}


/* news */

section#news {
    /* background-color: #f7f8f9; */
}

div.news-table-frame {
    /* height: 128px;
    height: 240px; */
    max-height: 240px;
    background-color: #fff;
    border: 1px solid #ced4da;
    overflow: auto;
    /*line-height: 1.6;*/
    /*padding-top: 1rem;*/
    margin-bottom: 1rem;
    /*margin-top: 0.5rem;*/
}

.news-table-frame table tr:last-child th,
.news-table-frame table tr:last-child td {
    /*border-bottom: 1px solid #ced4da;*/
    /* Bootstrapの標準色 */
}

div.news-table-frame table {

    margin-bottom: 0;
    /*margin-top: 0.5rem;*/
}


div.news-table-frame table th {

    vertical-align: middle;
    font-weight: 500;
    white-space: nowrap;
    color: #6c757d !important;
}


div.news-table-frame table tr,
div.news-table-frame table th,
div.news-table-frame table td {
    border-style: dotted;
    vertical-align: middle;
}
div.news-table-frame table th.new-news::after {
    content: "NEW";
    background-color: red;
    color: white;
    font-size: 0.6em;
    font-weight: bold;
    padding: 2px 6px;
    margin-left: 8px;
    border-radius: 4px;
    vertical-align: middle;
    display: inline-block;
}

div.news-table-frame table tr {
    /*border-left: none;*/
    /*border-right: none;*/
}

div.news-table-frame table tr:first-child {
    border-top: none;
}

div.news-table-frame table tr:last-child {
    /*border-bottom: none;*/
}


table.news-table {
    font-size: 16px;
    font-size: 1rem;
    font-size: 0.9rem;
    margin: 0;
    vertical-align: middle;
}

table.news-table th {
    white-space: nowrap;
    text-align: right;
    padding-right: 1.25rem;
    padding-left: 1.25rem;
}


/* features */

section#features {
    /*background-color: #fff;*/
}

.features-title h3 {
    font-size: 23px;
    font-size: 1.4375rem;
    font-weight: 600;
    color: #333;
}

.features-detail {
    font-size: 16px;
    font-size: 1rem;
    font-weight: 400;
    color: #8b8b8b;
}


/* statistics */

section#statistics {
    /*background-color: #f0f9fe;*/
}

.statistics-name h3 {
    font-size: 23px;
    font-size: 1.4375rem;
    font-weight: 600;
    color: #333;
    white-space: nowrap;
}

.statistics-number {
    font-size: 48px;
    font-size: 3rem;
    font-size: 2.25rem;
    font-weight: 400;
    font-weight: 500;
}


/* data-source */

section#data-source {
    /*background-color: #fff;*/
}

#data-source ul {
    list-style-type: none;
}

#data-source ul li {
    font-size: 16px;
    font-size: 1rem;
    font-weight: 600;
    color: #333;
}

#data-source ul li a {
    font-size: 20px;
    font-size: 1.25rem;
    font-weight: 600;
}

#data-source ul.data-source-list1 li small {
    font-size: 1rem;
    font-weight: 500;
}

#data-source ul.data-source-list2 li small {
    font-size: 1.125rem;
    font-weight: 600;
}



section#data-source .data-source-mobile .section-title h2 {
    margin-bottom: 0;
}

main h2 small {
    font-size: 1rem;
    font-size: 1.5rem;
}

section#data-source .data-source-mobile .tab-content {
    /*background-color: #fff;
    border-radius: var(--bs-border-radius);*/
    border-width: 1px !important;
}

/*section#data-source .data-source-mobile-word img,*/
section#data-source .data-source-pc-word img {
    max-width: 546px;
}


.data-source-mobile-word label,
.data-source-pc-word label {
    width: 7rem;
    white-space: nowrap;
    text-align: right;
}

.data-source-mobile-word .row,
.data-source-pc-word .row {
    --bs-gutter-x: 1rem;
    --bs-gutter-x: 0.75rem;
}

/*.modal select,
.modal input,*/
/*#list-tab-pane select,*/
.blog-sidebar select,
.blog-sidebar input,
#data-source select,
.data-source-mobile-map select,
.data-source-pc-map select,
.data-source-mobile-word input,
.data-source-pc-word input,
.data-source-mobile-word select,
.data-source-pc-word select {
    background-color: #F0F8FF !important;
    background-color: #f5f8ff !important;
}


.data-source-pc-map-typea .btn {
    /*width: 12rem;*/
    padding-left: 1rem;
    padding-right: 1rem;
}

/* link */


#link .card a p.card-title-detail {
    font-size: 0.9rem;
    color: rgba(var(--bs-secondary-rgb), var(--bs-text-opacity)) !important;
    color: #6c757d !important;
    font-weight: 400;
    display: none;
}

/* disclaimer */

section#disclaimer {
    background-color: #fff;
}


section#disclaimer p,
section#disclaimer ul {
    /* font-size: 0.9rem; */
    font-size: 1rem;
}

/* icon image */

.features-image,
.statistics-image,
.data-source-image {
    /*margin-bottom: 30px;
    margin-bottom: 30px;*/
    width: 145px;
    height: 145px;
    margin: 0 auto;
    border-radius: 50%;
    border: 10px solid #e2e2e2;
    margin-bottom: 16px;
    transition: all 0.2s ease-in-out;
    background-position: center;
    background-repeat: no-repeat;
    background-size: 145px;
}





/* fix */
section#main-banner .col-6 {
    flex-basis: content;
}

section#main-banner h1.main-title {
    font-size: 120px;
    font-size: 6rem;
    margin-bottom: 0.5rem;
    line-height: 6rem;
}

section#main-banner p.main-subtitle {
    margin-bottom: 3rem;
    margin-bottom: 2.4rem;
}

section#main-banner p.main-subtitle {
    font-size: 1rem;
    letter-spacing: normal;
}

html:lang(en) section#main-banner p.main-subtitle {
    font-size: 0.9rem;
}

section#main-banner div .btn-disease,
section#main-banner div .btn-drug {
    width: 192px;
    width: 200px;
}

section#main-banner div .btn-dna {
    width: 294px;
    width: 320px;
}

section#main-banner div.main-search .input-group {
    max-width: 420px;
}

html:lang(en) section#main-banner div .btn {
    font-size: 1.0rem;

}

section#main-banner div .btn span {
    margin-left: 0.05rem;
    margin-right: 0.05rem;
}

html:lang(en) section#main-banner div .btn span {
    font-size: 0.9rem;
    margin-left: 0.25rem;
    margin-right: 0.25rem;
}


section#main-banner div.main-search input::placeholder {
    font-size: 1.0rem;
}

html:lang(en) section#main-banner div.main-search input::placeholder {
    font-size: 0.9rem;
}

section#main-banner div.main-search.mb-5 {
    margin-bottom: 2.4rem !important;
}



/* Print */
@media print {
    .fadeIn_up {
        opacity: 1;
        transform: translateY(0);
    }

    section {
        padding-top: 2.5rem;
    }

}

/* footer */

footer div.container {
    /*max-width: 540px;*/
}


/* Small devices (landscape phones, 576px and up) */
@media (min-width: 576px) {
    section#main-banner div.main-search input::placeholder {
        color: transparent;
    }

    section {
        padding-top: 3.0rem;
    }

    section#main-banner div.d-xl-block {
        display: none;
    }

    footer div.container {
        /*max-width: 540px*/
        ;
    }
}

/* Medium devices (tablets, 768px and up)*/
@media (min-width: 768px) {
    section#main-banner div.main-search input::placeholder {
        /*color: #8b8b8b;*/
        color: transparent;
    }

    section {
        padding-top: 3.0rem;
    }

    section#main-banner div.d-xl-block {
        display: none;
    }

    footer div.container {
        /* max-width: 720px;*/
    }
}

/* Large devices (desktops, 992px and up)*/
@media (min-width: 992px) {
    section#main-banner div.main-search input::placeholder {
        color: #8b8b8b;
    }

    section {
        padding-top: 3.0rem;
    }

    section#main-banner div.d-xl-block {
        display: none;
    }

    footer div.container {
        /*max-width: 960px;*/
    }

    .navbar-expand-lg {
        height: 56px;
    }
}

/* Extra large devices (large desktops, 1200px and up)*/
@media (min-width: 1200px) {

    .container,
    .container-lg,
    .container-md,
    .container-sm,
    .container-xl {
        max-width: 1200px;
        max-width: 1140px;
    }

    section {
        padding-top: 3.5rem;
    }

    section#main-banner div.d-xl-block {
        display: block;
    }

    footer div.container {
        /*max-width: 1200px;*/
    }
}


/**/


/*トップメイン汎用ボタン*/
.contents-main .card-body {
    border: none;
}

.contents-main .card-image {
    overflow: hidden;
    position: relative;
    /*border-radius: 3px;*/
    margin-bottom: 1rem;
}

.contents-main .card-image img {
    max-width: 100%;
    height: auto;
    border-radius: 3px;
    border-radius: 0.8rem;
}

.contents-main .card-title {
    font-weight: 500;
    line-height: 1.45;
    text-align: center;
}


/* contents-main */

.contents-pickup .card,
.contents-side .card,
.contents-main .card {
    border: 3px solid #e2e3e5;
    border: none;
    border-radius: 0;
    /*margin-bottom: 1rem;*/
    transition: all 0.3s ease;
}


.contents-main .card-body {
    /*border: 3px solid #e2e3e5;*/
}

.contents-pickup .card:hover,
.contents-side .card:hover,
.contents-main .card:hover {
    opacity: 0.75;
    opacity: 0.6;
}

.contents-pickup .card i,
.contents-pickup .card a,
.contents-side .card i,
.contents-side .card a,
.contents-main .card i,
.contents-main .card a {
    color: #383d41;
}

.contents-main .card i {
    /*margin-bottom: 1rem;*/
}

.contents-pickup .card-title,
.contents-side .card-title,
.contents-main .card-title {
    /*margin-bottom: 0;*/
}

/* link */

main a {
    color: #007bff;
    color: #306FBB;
    /*color: #2792C3;*/
    /*color: var(--theme-color1);*/
    color: var(--link-color1);
    text-decoration: none;
    background-color: transparent;
}

main a:hover {
    color: #0056b3;
    color: #cc0033;
    /*text-decoration: underline;*/
}

main a:hover img {
    opacity: 0.75;
}

main a:hover {
    /*opacity: 0.6;*/
    text-decoration: none;
}

main a {
    transition: all 0.3s ease;
}


.disabled-link {
    pointer-events: none;
    cursor: default;
    color: gray;
}